Using tretinoin correctly ensures the best results while minimizing irritation. This formula is designed to last three months, based on using ¼ to ½ a pump per once-daily application. Since tretinoin is powerful, using more than recommended won’t speed up results but may cause dryness, peeling, and irritation. Less is more—a small amount is all you need for long-term improvements.

When starting treatment, begin with once per week, then gradually increase to every third night, then every other night, and finally nightly use as tolerated.