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Functions of Estrogen, Progesterone, and DHEA

Learn how estrogen, progesterone, and DHEA function in the body and the benefits of using them in hormone replacement therapy (HRT).

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Written by Patient Care
Updated this week

Estrogen Replacement

Estrogen plays a role in many systems in the body, including metabolism, heart, bone, and brain function. Estrogen replacement therapy alleviates both physical and mental symptoms of the menopause transition.

Benefits of estrogen replacement therapy include:

  • Reduced hot flashes & night sweats

  • More restful, uninterrupted sleep

  • Reduced hormonal weight gain

  • More even, stable moods

  • Increased energy

  • Better focus, memory, and concentration

  • Reduced hip & joint pain

  • Support for long-term bone, heart, cognitive, and metabolic health

Progesterone Replacement

Progesterone plays a vital role in balancing estrogen levels and maintaining endometrial health during the menopause transition.

Benefits of progesterone replacement therapy include:

  • Reduced vasomotor symptoms (hot flashes, night sweats)

  • Improved sleep

  • Promotion of healthy uterine lining

  • Reduced irregular bleeding

  • Support for long-term bone, heart, cognitive, and metabolic health

DHEA Replacement

DHEA is a safer, more effective way for women to raise testosterone levels. Testosterone is also key in women’s health. Testosterone levels in women impact bone and muscle health, memory and brain function, energy levels, and libido. DHEA is a precursor hormone the body uses to create testosterone.

Benefits of DHEA replacement therapy include:

  • Increased energy levels

  • Improved metabolism

  • Enhanced libido

  • Stronger memory & cognitive function

  • Protection of bone strength

  • Improved skin health & collagen production

  • Promotion of healthy muscle mass

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