Important Distinction Between HRT and GLP-1 Medications for Weight Loss
HRT and GLP-1 medications are two distinct treatments with separate purposes. While both can help with weight loss, they work differently in the body and treat different types of weight concerns.
HRT Treatments
How HRT Works:
HRT treats over 100 possible symptoms related to the menopause transition by restoring hormone levels in the body that decline with age.
HRT does treat weight changes specifically related to the menopause transition.
During this time, the body’s metabolism can slow, and existing fat distribution can shift primarily to the abdomen. HRT can reduce new hormonal weight gain by improving the metabolism and reverse changes in fat distribution.
HRT does not treat unrelated, non-hormonal weight gain.
HRT restores hormone levels, so it cannot treat chronic obesity or other lifelong weight issues not rooted in hormonal changes.
GLP-1 Medications
How GLP-1 Medications Work:
GLP-1 medications influence insulin production, glucagon release, and gastric emptying. Related to weight loss, these medications keep food in the stomach longer by slowing digestion, promoting a prolonged feeling of fullness.
GLP-1 medications do treat chronic obesity.
When used for weight loss, GLP-1 medications are mostly prescribed to address obesity or those with lifelong weight issues.
GLP-1 medications do not treat weight changes that occur as a result of the menopause transition.
Since hormonal decline is the root cause of that type of weight gain, GLP-1 medications will not specifically target it.
Is it safe to use a GLP-1 medication with HRT?
Yes, because these medications work through completely different mechanisms, it’s safe to use both at the same time. If you’re seeking to address hormonal weight changes and other types of weight gain or chronic obesity, you may benefit from both treatments.