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Different Functions of Hormones
Different Functions of Hormones

Is hormone replacement therapy safe?

Jo Cullen avatar
Written by Jo Cullen
Updated over 2 months ago

When monitored and guided by trained medical professionals, HRT can improve the health and well-being of women going through the menopause transition. The hormones that are prescribed each play a different role in managing symptoms.

What you should know:

  1. Estrogen Replacement: Estrogen has many jobs, but an important one is mental processing; Estrogen lubricates the brain. Taking HRT in menopause may improve memory, concentration, and cognition. Estrogen can help protect against heart disease, stroke, and decrease blood cholesterol, and it can lower the incidence of Alzheimer’s/dementia. It has also been shown to improve mood swings, decrease water retention, reduce hot flashes, prevent osteoporosis, and reduce the chance of Type 2 diabetes.

  2. Progesterone Replacement: Once a woman reaches her late 30s or early 40s, she'll likely enter perimenopause, and progesterone production starts to decline. Once she reaches menopause, circulating progesterone levels are so low, they are similar to levels normally seen in men. Research shows that supplementing progesterone can improve brain function, mood, and cardiovascular and nervous system health. Progesterone can protect against uterine and breast cancer, support the metabolism, normalize blood sugar, reverse osteoporosis, improve thyroid function, reduce anxiety, and act as a natural antidepressant.

  3. Testosterone Replacement: Although many think of it as a male hormone, testosterone is also an important female hormone that plays a critical role in women’s health. Testosterone maintains normal metabolic function, muscle and bone strength, urogenital health, mood, and cognitive function. A testosterone deficiency can lead to low sexual desire, arousal, and orgasm. Tiredness, depression, headaches, cognitive problems, osteoporosis, and lean body tissue loss are additional complications from low testosterone. Testosterone levels peak in a woman’s 20s and start to decrease years before perimenopause. By menopause, most women’s levels are half of their peak levels. Winona offers DHEA, a testosterone precursor, to gently replace waning testosterone.

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